Our genes affected by epigenes? Who knew? I was rereading an earlier blog I’d posted about Angelina Jolie’s choice to remove her breasts prophylactically because of her trusting the bad advice that her compromised genes should dictate this action. I felt that some of the info deserved repeating. Here is the gist of the article by Sayer Ji at GreenMedInfo.com in my previous blog that, despite so-called ‘evidence-based medicine,’ acknowledges the most current evidence of genetics.
Basically he states that, following the completion of the first draft of the entire human genome in 2000, the central dogma of molecular biology – that our DNA controls protein expression, and therefore disease risk – was disproved. Our genome was found to contain roughly only 20,000 genetic instructions – not even enough to account for the 100,000 proteins in the human body!”
As a result, we now know that the field of epigenetics or ”Junk genes,” is much more important than genes. Epigenetic factors are influenced by a combination of nutrition, lifestyle factors, environmental exposures, and psychospiritual states that feed back into our physiology. They constitute as high as 95% of what determines any disease risk. In fact, ”even the psychological trauma associated with being diagnosed with cancer is enough to drive a malignancy via adrenaline-mediated multi-drug resistance, and according to a recent NEJM study, leads up to a 26-fold increased risk of heart-related deaths in the seven days following diagnosis.” ETH Zurich. “Epigenetics: DNA Isn’t Everything.” ScienceDaily. ScienceDaily, 13 April 2009. . In other words, our mental/emotional state can influence directly the physiological activity of healthy and cancerous cells, more than our inherited ancestral genes.